Microplate Evaporators

 

Porvair evaporators are designed to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates prior to analysis or reconstitution in storage buffer. These evaporators give significant throughput advantages to laboratories looking to optimise microplate sample preparation productivity. Faster than centrifugal evaporation, significant increases in sample throughput are achieved through advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each individual well of the microplate simultaneously. The evaporators have been designed to be simple to install, operate and maintain. Installation requires only connection to a gas supply or cylinder and mains electricity. Safety of operation is ensured as the CE marked compact units fit into all fume cupboards. Not suitable for high boiling solvents such as DMSO and water. Both MiniVap and UltraVap may be operated with a supply of clean, dry compressed air in place of nitrogen, if the chemistry allows. An in-line gas filter must be used in this case.

 


 

 

MiniVap™

MiniVap

The MiniVap is purpose designed for low usage research and development departments where low numbers of individual plates or vials need drying. The MiniVap is simple to operate and maintain. Installation requires only connection to a gas supply and standard mains socket. With manual control of the needle depth, gas temperature and flow rate, it allows fine control and quicker drying times than other standard methods.

Porvair Sciences announces new versions of its MiniVap and UltraVap blowdown evaporators that use warm air or nitrogen to speed up the evaporation of common HPLC solvents such as dichloromethane, methanol and acetonitrile from sample vials, significantly improving throughput and removing this common laboratory bottleneck.

Combining a new 48-well needle head with a dedicated HPLC vial holder that accepts 48 standard 1.5ml vials* transforms any MiniVap or UltraVap system into a high throughput HPLC sample evaporator. Applications that will benefit from the new HPLC sample evaporators include pre-concentration prior to injection (to increase sensitivity) as well as evaporation to dryness of post-column fractions for recovery of compounds.

 

● Quicker dry down times than standard methods such as vacuum oven

● Tests have shown that the MiniVap can evaporate 500μl of methanol in less than 6 minutes

● Designed for any SBS/ANSI 96 well plate

● 24 vial head now available

● Simple to install and operate

● Easy adjustments of temperature, gas flow rates and needle depth into the wells

● Compact footprint – fits all standard fume cupboards


 

 

Ultravap™

 

Whereas the MiniVap™ is a fully manual system, the Ultravap™ is a digitally controlled programmable evaporator. It can be used as a stand alone unit or driven by a computer, often connected to a robotic liquid handler. After empirical data for dry down has been produced, this can be entered into the memory of the Ultravap for future recall and use. Each programme has three stages, with control of gas temperature, pressure and plate height at each stage. Nine different methods can be permanently stored in memory. The Ultravap will then evaporate plate contents quickly, by keeping the heated gas needles close to the liquid surface at all times in the concentration process, without further manual intervention.

Porvair Sciences announces new versions of its MiniVap and UltraVap blowdown evaporators that use warm air or nitrogen to speed up the evaporation of common HPLC solvents such as dichloromethane, methanol and acetonitrile from sample vials, significantly improving throughput and removing this common laboratory bottleneck.

Combining a new 48-well needle head with a dedicated HPLC vial holder that accepts 48 standard 1.5ml vials* transforms any MiniVap or UltraVap system into a high throughput HPLC sample evaporator. Applications that will benefit from the new HPLC sample evaporators include pre-concentration prior to injection (to increase sensitivity) as well as evaporation to dryness of post-column fractions for recovery of compounds.

 

● Designed for heat sensitive and thermally labile samples

● Nine different drying programmes can be retained in the memory

● Ability to upload and download methods

● Robotic plate stage automatically moves plates up and down

● RS232 allows remote control via PC or LH robot

● Removes most stubborn solvents in just minutes

● Can evaporate 500μl methanol in 5 minutes

● Compact footprint allows the Ultravap to fit into all standard fume cupboards

● Choice of straight, curved & 24, 96 or 384 needles

● Compatible with Tecan™, Hamilton™ and Beckman™ robotic liquid handlers


 

Ultravap Mistral

Mistral

 

  • Fully liquid handling robot compatible dry down station
  • Plate shuttle sends/retrieve plates from robot deck
  • Adjustable shuttle position and height
  • Intuitive graphical colour touch screen display
  • Up to 30 stored evaporation programmes
  • Up to 5 programmable steps per method
  • On board gas management
  • Master & multiple slave configuration supported
  • Remote control from PC option
  • Reversible screen for integration at side of robot
  • Built in fume management and duct connector
  • Faster evaporation times
  • Choice of 384, 96, 48 & 24 well heads
  • Small footprint to fit in your hood


The Ultravap Mistral from Porvair Sciences is designed to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates.
It is our most sophisticated automation-friendly model yet, giving significant throughput advantages to laboratories looking to optimise microplate sample preparation. Faster than centrifugal evaporation for single plates, significant increases in sample throughput are achieved through advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each individual well of the microplate simultaneously. Installation requires only connection to a gas supply and mains electricity. Safety of operation is ensured as this CE-marked compact unit fits into all fume cupboards and boasts full integral fume management within the unit.

The UltraVap Mistral may be operated with a supply of clean, dry compressed air in place of nitrogen, if the chemistry allows. An in-line gas filter must be used in this case. The new Ultravap Mistral is the latest fully robotcompatible nitrogen blow-down evaporator, suitable for integration adjacent to several leading laboratory liquid handling robots. Designed with the demands of linear robots very much in mind, the Ultravap Mistral offers a plate shuttle which can serve and retrieve plates from the deck of Perkin Elmer, Tecan, Hamilton and Beckman liquid handlers. The colour touch-screen controlled dry down station accepts 24-, 48-, 96- or 384-well plates and comes complete with clear safety side screens and integral fume management leading to a 4 inch duct adaptor.
Flexible programming

The Ultravap Mistral has been designed to allow robots with standard gripper arms to place and remove microplates directly onto the shuttle. In comparison with previous models, the Ultravap Mistral has a 10% smaller footprint, allowing better access and saving valuable bench space.
The evaporation table is able to rise under the control of a stepper motor as the drying process proceeds. This can be programmed at a suitable rate for each solvent type being evaporated. In addition, gas temperature, pressure and flow rate can all be programmed individually and stored in up to thirty multistep programmes on the Ultravap Mistral controller. Each programme allows the table to rise in up to five distinct ramped phases, so that a fast initial drying period can be followed by a gentler final drying phase. The new Ultravap Mistral lends itself to full integration with most robotic liquid handlers, where it is usually located on the right-hand side of the deck. Control commands are sent directly from the robot controller to the Ultravap. These standard commands are listed in the manual, but most robot manufacturers have drivers available to control the Ultravap, making integration a seamless process.

Solvent compatibility
With a choice of 96 straight or 96 spiral needles, plus 24,
48 and 384 straight needles, the sphere of application for With a choice of 96 straight or 96 spiral needles, plus 24,
48 and 384 straight needles, the sphere of application for Ultravap Mistral is huge. Most common chromatography solvents can be evaporated with ease, such as dichloromethane, methanol, acetonitrile and hexane. The nitrogen blow-down method is not, however, suitable for high-boiling point solvents such as DMF, DMSO and water. It is also unable to be used with acids or acid chlorides, as special corrosion-resistant systems are needed for this work. The choice of straight or spiral needles allows the user to choose between faster dry down (spiral) and better final drying in V-well plates (straight). The spirals cause a vortex to form in the solvent, increasing the surface area and thus speeding up the rate of evaporation.


Evaporator System Requirements
Gas flow rate: 28L/min minimum, 80L/min maximum at
6 bar pressure. Can be used with nitrogen or dry compressed air if the chemistry allows. Not suitable for use with strong acids or acid chlorides.

Joomla Template: from JoomlaShack