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SiliaSep™ cartridges are compatible with every commercially available system.

Use the superior performance of our UltraPure SiliaFlash® and SiliaBond® silica gels in all your separations with our pre-packed SiliaSep™ cartridges. You can increase the reproducibility of your separations by using the same silica gel for all your flash systems.

SiliCycle® offers a full line of cartridges compatible with existing technologies: Isco™ (SiliaSep™), Biotage™ (SiliaSep™ BT), FlashMaster™ (SiliaSep™ OT) and Büchi™ (SiliaSep™ BU) systems. Our Special Holder--->

By using our SiliaSep™ cartridges, you will not only save time and money but you will also generate higher purity samples and reduce the number of false positives in your screening, resulting in higher quality data. All our flash cartridges are packed with sorbents based on our fines-free UltraPure SiliaFlash® silica gel which has the highest purity on the market. When using our SiliaSep™cartridges, we guarantee you the following benefits:

- Excellent packing and storage qualities
- Very good separation and tighter peaks
- Less time and solvent spent conditioning the cartridge
- No silica contamination in your final product
- Higher recoveries Highly controlled pH, water and metal content from lot-to-lot
- Reproducible and faster flow rate Wide variety of sorbents available (SiliaBond® phases)

To better suit your needs, SiliCycle® SiliaSep™ cartridges are available in a wide variety of sorbents: normal phase, reversed-phase, ion exchanger, and fluorous phase. The hydrophobicity of the sorbent is an important parameter when selecting the sorbent. As a general rule, the stationary phase hydrophobicity decreases as follow:

SiliaSep™ cartridges characteristics
Our cartridges present a high purity alternative to the other cartridges available on the market. SiliCycle®’s cartridges are 100% compatible with commercially available systems. All our SiliaSep™ flash cartridges are packed with SiliaFlash® F60 (40-63µm, 60Å) as standard sorbent. You will have great value because our cartridges present the following advantages:

Characteristics of SiliaSep™ Cartridges
- Very high purity and quality silica gels
- Clean, pre-packed, disposable polypropylene (or high density polyethylene) cartridges
- Leak-free guaranteed
- Choice of many types of packing
- Choice of pore sizes and particle size diameters
- Choice of bonded phases (SiliaBond® phases): C18, Amine, Cyano, Diol, Fluorochrom and SCX-2 scavengers and other phases available upon request
- Faster separations with improved band definition
- Safe: No glass handling or washing, No breakage
- Excellent pricing and volume discounts available
- Readily available from inventory for many volumes

SiliaSep™ (universal closed top luer-lock cartridges)
Isco™ Compatible SiliaSep™ available silica weights:
4 g - 120 g
12 g - 220 g
25 g - 330 g
40 g - 750 g
80 g - 1500 g
Also available: SiliaSep™ HP, packed with our UltraPure small particle SiliaFlash®.

SiliaSep™ BT Biotage™ i Compatible
SiliaSep™ BT available sizes: - 12S and 12M
- 40S, 40M and 40L
- 65
- 75S, 75M and 75L


SiliaSep™ BU Büchi™ Compatible

SiliaSep™ BU available sizes:
- 12S and 12M
- 40S and 40M


SiliaSep™ OT FlashMaster™ Compatible
SiliaSep™ OT available silica weights:
- 2, 5, 10, 15, 20, 25, 50, 70, 100 and 200 g
- Other sorbent weights are available upon request


SiliaSep™ OT column volumes:

- 12, 25, 70, 150, 276 and 377 mL

Empty Cartridges for Self Packing.


Our flash chromatography products offer high levels of performance and reproducibility. The flash media consistently has a tight particle size distribution with low fines and extremely low metal ion content, for more predictable and easier separations.

Using SiliCycle® SiliaSep™ cartridges, you can purify your sample based on different mechanisms depending on the properties of your compound. Because we can provide cartridges packed with our SiliaBond® functionalized silica gel, you can choose exactly the cartridge that will fit your need. The chart below is designed to serve as a guide in sorbent selection by considering the characteristics of your sample.